Cryo Blast is also great, especially if Shepard and another squad member can take down the defenses of multiple enemies in unison. Incineration Blast can take off the armor of up to three enemies at a time in a single hit.
On harder difficulties I would say at least 75% of the enemies in the game have armor. Mordin's Incinerate is great at taking down armor. Give him a spot to sit at and he is great at shooting enemies with his sniper rifle better than most of your other squad members. Thane is also great at dealing out pure damage. These characters have the most utility with the amount of damage they can deal and how quickly defenses can be taken down. These decisions are also based on playing Hardcore or Insanity difficulty.įrom the data above, you can see that I use Miranda, Mordin, Thane, and Zaeed the most. Some choices will depend on what class your Shepard is, but this is a pretty broad and general set of suggestions that are the most useful.